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Hanumantha Rao Balaji Raghavendran

Hanumantha Rao Balaji Raghavendran

Hanumantha Rao Balaji Raghavendran

MS, PhD National Orthopaedic Centre of Excellence in Research and Learning (NOCERAL), Department of Orthopaedic Surgery Malaysia

BIOGRAPHY 4 PUBLICATIONS 62

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EDUCATION

Doctor of Philosophy, Biochemistry: 2005-Department of Biochemistry, University of Madras, India.

Master of Science, Biochemistry: 2001-Vysya College, Affiliation: Periyar University, Salem District, India. 

Bachelor of Science, Biochemistry: 1998-Vysya College, Affiliation: University of Madras, India.

  • Hanumantha Rao Balaji Raghavendran is Skilled and results-oriented professional with academic preparation holding a University Madras Ph.D degree (Biochemistry) and experience in in vitro and in vivo research seeks Associate Professor Position in esteemed university. Proven ability to assess and strong trouble shooter. Successful in intense and demanding environments providing decisive team leadership and structure with a tract record research papers on material engineering and stromal cells for Orthopaedic and Herbal research applications. 
  • Hanumantha Rao Balaji Raghavendran Joined his Post-doctoral fellowship in South Korea, in POSTEC, Intracellular communication lab, followed by a Post-doc fellowship for 4 years in Korean Atomic Energy Research Institute. One year as research associate in Sri Ramachandra University at HIMRL lab 2008 to 2009. In following year received post-doctoral fellowship grant from Liver and Immunology Laboratory South Korea. Since 2009 to 2013 as a Senior research scientist in NOCERAL and from 2013 to date as Associate Professor NOCERAL, Tissue engineering lab, University Malaya.
  • Hanumantha Rao Balaji Raghavendran, published 71 research articles for his research credit and since 8 years major focus on application of biomaterials for bone tissue engineering applications.
  • Nida Iqbal, Hanumantha Rao Balaji Raghavendran et al., Zinc-doped hydroxyapatite-zeolite/polycaprolactone composites coating on magnesium substrate for enhancing in-vitro corrosion and antibacterial performance. Transactions of Nonferrous Metals Society of China ( In Press).
  • Salma Baig, Ainnul Hamidah Syahadah Azizan, Hanumantha Rao Balaji Raghavendran, Elango Natarajan , Sangeetha Naveen, Malliga Raman Murali, Hui Yin Nam, Tunku Kamarul. Effect of Chitosan Nanoparticle-Loaded Thymus serpyllum on Hydrogen Peroxide-Induced Bone Marrow Stromal Cell Damage Stem Cells Int. 2019 Feb 26;2019:5142518.
  • Krishnamurithy G, Mohan S, Yahya NA, Mansor A, Murali MR, Raghavendran HRB, Choudhary R, Sasikumar S, Kamarul T. The physicochemical and biomechanical profile of forsterite and its osteogenic potential of mesenchymal stromal cells. PLoS One. 2019 Mar 27;14(3):e0214212. (ISI-Indexed).
  • Mohan S, Raghavendran HB, Karunanithi P, Murali MR, Naveen SV, Talebian S, Mehrali M, Mehrali M, Natarajan E, Chan CK, Kamarul T. Incorporation of Human-Platelet-Derived Growth Factor-BB Encapsulated Poly(lactic-co-glycolic acid) Microspheres into 3D CORAGRAF Enhances Osteogenic Differentiation of Mesenchymal Stromal Cells. ACS Appl Mater Interfaces. 2017 Mar 22; 9(11):9291-9303. 
  • Vattam KK, Raghavendran HRB, Murali MR, Savatey H, Kamarul T. Coadministration of alloxan and nicotinamide in rats produces biochemical changes in blood and pathological alterations comparable to the changes in Type II diabetes mellitus. Human and Experimental Toxicology. Oct 2015. (ISI/SCOPUS Indexed Publication).
  • Zeimaran E, Mohan S, Pourshahrestani S, Murphy BP, Kadri NA, Murali MR, Raghavendran HRB, Hasikin K, Kamarul T, Towler MR. 2016. Osteogenic differentiation of mesenchymal stem cells on a poly (octanediol citrate)/ bioglass composite scaffold in vitro. Materials & Design. 109; 434-442. (ISI/SCOPUS Indexed Publication).
  • Dashtdar H, Murali MR, Selvaratnam L, Balaji Raghavendran H, Suhaeb AM, Ahmad TS, Kamarul T. (2016). Ultra-structural changes and expression of chondrogenic and hypertrophic genes during chondrogenic differentiation of mesenchymal stromal cells in alginate beads. PeerJ 4:e1650 (ISI-Indexed).
  • Puvaneswary S, Balaji Raghavendran H, Talebian S, Murali MR, Mahmod SA, Singh S, Kamarul T. (2016). Incorporation of Fucoidan in ß-Tricalcium phosphate-Chitosan scaffold prompts the differentiation of human bone marrow stromal cells into osteogenic lineage. Scientific Reports. 6, 24202. (ISI-Indexed).
  • Choudhary R, Vecstaudza J, Krishnamurithy G, Raghavendran HRB, Murali MR, Kamarul T, Swamiappan S, Locs J. 2016. In-vitro Bioactivity, Biocompatibility and Dissolution Studies of Diopside prepared from Biowaste by using Sol-Gel Combustion Method. Materials Science and Engineering C. 68:89-100. (ISI/SCOPUS Indexed Publication).
  • Balaji Raghavendran HR, Saktiswaren, Genesan K, Murali MR, Naveen SV, Talebian S, McKean R, Kamarul T. Synergistic interaction of platelet derived growth factor (PDGF) with the surface of PLLA/HA/Col and PLLA/HA scaffolds produces rapid osteogenic differentiation. Colloids and Surfaces B: Biointerfaces. 2016; 139: 68 78. (ISI-Indexed).
  • Krishnamurithy G, Yahah NA, Mehrali M, Mehrali M, Mohan S, Murali MR, Raghavendran HRB, Kamarul T. 2016. Effects of carbon doping on the microstructural, micro/nano-mechanical, and mesenchymal stromal cells biocompatibility and osteogenic differentiation properties of alumina. Ceramics International. 42(16), 18247-18256. (ISI-Indexed).
  • Ibrahim MR, Singh S, Merican AM, Raghavendran HR, Murali MR, Naveen SV, Kamarul T. (2016). The effect of strontium ranelate on the healing of a fractured ulna with bone gap in rabbit. BMC Veterinary Research.12(1), 112. (ISI-Indexed).
  • Karunanithi P, Murali MR, Samuel S, Raghavendran HB, Abbas AA, Kamarul T. 2016. Three dimensional alginate-fucoidan composite hydrogel augments the chondrogenic differentiation of mesenchymal stromal cells. Carbohydrate polymers. 147: 294–303. (ISI/SCOPUS Indexed Publication).
  • Nida Iqbal, M.R. Abdul Kadir, Saman Iqbal, Saiful Izwan Abd Razak, M. Shahid Rafique, H.R. Bakhsheshi- Rad, Mohd. Hasbullah Idris, M.A. Khattak, H.R. B. Raghavendran, AA Abbas. 2016. Nano-hydroxyapatite reinforced zeolite ZSM composites: A comprehensive study on the structural and in vitro biological properties. Ceramics international. (ISI/SCOPUS Indexed Publication).
  • Naveen SV, Irene TKP, Shan GY, Balaji Raghavendran HR, Murali MR, Kamarul T. 2015. Unmodified medium chain length polyhydroxyalkanoate (uMCL-PHA) as a thin film for tissue engineering application characterization and in vitro biocompatibility. Materials Letters. 141; 55-58. (ISI/SCOPUS Indexed Publication).
  • Chidamabaram SB, Pandian A, Sekar S, Haridass S, Vijayan R, Thiyagarajan LK, Ravindran J, Balaji Raghavendran HR, Kamarul T. Sesame indicum, a nutritional supplement, elicits antiamnesic effect via cholinergic pathway in scopolamine intoxicated mice. Environ Toxicol. 2015 (ISI/SCOPUS Indexed Publication).
  • Puvaneswary S, Talebian S, Balaji Raghavendran HR, Murali MR, Mehrali M, Afifi AM, Kamarul T. Fabrication and in vitro biological activity of Fucoidan-chitosan- TCP composite for bone tissue engineering. Carbohydrate polymers. (ISI/SCOPUS Indexed Publication).
  • Krishnamurithy G, Murali MR, Hamdi M, Abbas AA, Raghavendran HB, Kamarul T. Proliferation and osteogenic differentiation of mesenchymal stromal cells in a novel porous hydroxyapatite scaffold. Regen Med. 2015 Aug;10(5):579-590. (ISI/SCOPUS Indexed Publication).
  • Iqbal N, AbdulKadir MR, Mahmood NH, Iqbal S, Almasi D, Naghizadeh F, Balaji HR, Kamarul T. 2015. Characterization and biological evaluation of silver containing fluoroapatite nanoparticles prepared through microwave synthesis. Ceramics International (ISI/SCOPUS Indexed Publication).
  • Talebian S, Mehrali M, Mohan S, Balaji raghavendran HR, Mehrali M, Khanlou HM, Kamarul T, Afifi AM and Abass AA. Chitosan (PEO)/bioactive glass hybrid nanofibers for bone tissue engineering. RSC Adv., 2014,4, 49144-49152 (ISI/SCOPUS Indexed Publication).
  • Murali MR, Naveen SV, Son CG, Raghavendran HB. 2014. Current knowledge on alleviating Helicobacter pylori infections through the use of some commonly known natural products: bench to bedside. Integrative Medicine Research; 3 (3): 111-118. 
  • Kamarul T, Krishnamurithy G, Salih ND, Ibrahim NS, Raghavendran HRB, Suhaeb,AR and Choon DSK. Biocompatibility and Toxicity of Poly(vinyl alcohol)/N,O-Carboxymethyl Chitosan Scaffold. The Scientific World Journal. 2014, Article ID 905103, 7 pages (ISI-Indexed).
  • Iqbal N, Abdul Kadir MR, Mahmood NH, Mohammad Yusoff MF, Siddique JA, Salim N, Froemming GRA, Sarian MN, Balaji Raghavendran HR, Kamarul T. 2014. Microwave synthesis, characterization, bioactivity and in vitro biocompatibility of zeolite hydroxyapatite (Zeo HA) composite for bone tissue engineering applications. Ceramics International. (ISI/SCOPUS Indexed Publication).
  • Balaji Raghavendran HR, Puvaneswary S, Talebian S, Murali MR, Naveen SV, Krishnamurithy G, McKean R, Kamarul T. 2014. A Comparative Study on In Vitro Osteogenic Priming Potential of Electron Spun Scaffold PLLA/HA/Col, PLLA/HA, and PLLA/Col for Tissue Engineering Application. PLoS One. Aug 20;9(8):e104389. (ISI/SCOPUS Indexed Publication).
  • Subhan RA, Puvanan K, Murali MR, Raghavendran HRB, Shani S, Abdullah BJ, Abbas AA, Mohamed JA, Kamarul T. 2014. Fluoroscopy Assisted Minimally Invasive Transplantation of Allogenic Mesenchymal Stromal Cells Embedded in HyStem Reduces the Progression of Nucleus Pulposus Degeneration in the Damaged Interverbal Disc: A Preliminary Study in Rabbits. The Scientific World Journal. (ISI-Indexed).
  • Iqbal N, Abdul Kadir MR, Mahmood NH, Salim N, Froemming GRA, Balaji HB, Kamarul T. 2014. Characterization, antibacterial and in vitro compatibility of zinc silver doped hydroxyl apatite nanoparticles prepared through microwave synthesis. Ceramics International. 40:4507 4513. (ISI-Indexed).
  • Krishnamurithy G, Murali MR, Hamdib M, Abbas AA, Raghavendran HB and T Kamarul. 2014. Characterization of bovine-derived porous hydroxyapatite scaffold and its potential to support osteogenic differentiation of human bone marrow derived mesenchymal stem cells. Ceramics International. 40: 771-777. (ISI-Indexed).
  • Puvaneswary S, Rao Balaji Raghavendran H, Ibrahim NS, Murali MR, Merican AM, Kamarul T. 2013. A Comparative Study on Morphochemical Properties and Osteogenic Cell Differentiation within Bone Graft and Coral Graft Culture Systems. International Journal of Medical Sciences. 10(11):1608-1614 (ISI-Indexed).
  • Raghavendran HB, Sathyanath R, Kueg H, Son GC. 2013. Treatment of Korean Panax Ginseng against Cisplatin-Induced Toxicity in Rats Haematological and Histological Examination of Liver, Spleen and Kidney. Research and Reviews: A Journal of Toxicology 3 (2), 33-37 (Non-ISI/Non-SCOPUS).
  • R Sathyanath, BR Hanumantha Rao, HG Kim, JH Cho, CG Son. 2013. Saponin and non-saponin fractions of red ginseng ameliorate cisplatin-induced pica in rats. Pharmaceutical biology 51 (8), 1052-1060 (Non-ISI/Non-SCOPUS).
  • NS Ibrahim, G Krishnamurithy, HRB Raghavendran, S Puvaneswary, Min NW, Kamarul T. 2013. Novel HA-PVA/NOCC bilayered scaffold for osteochondral tissue-engineering applications–Fabrication, characterization, in vitro and in vivo biocompatibility study. Materials Letters 113, 25-29 (ISI/SCOPUS Indexed Publication).
  • Ab-Rahim S, Selvaratnam L, Raghavendran HR, Kamarul T. Chondrocyte-alginate constructs with or without TGF-ß1 produces superior extracellular matrix expression than monolayer cultures. Molecular and Cellular Biochemistry 2013 April; 376(1-2):11-20.
  • HRB Raghavendran, S Rekha, HKKJH Cho, SS Jang, CG Son. 2012. Ginsenoside rich fraction of Panax ginseng CA Meyer improve feeding behavior following radiation-induced pica in rats. Fitoterapia 83 (6), 1144-1150 (ISI/SCOPUS Indexed Publication).
  • HRB Raghavendran, R Sathyanath, JW Shin, HK Kim, JM Han, JH Cho, Son GC. 2012. Panax ginseng Modulates Cytokines in Bone Marrow Toxicity and Myelopoiesis: Ginsenoside Rg1 Partially Supports Myelopoiesis. PLoS ONE 7 (4), e33733 (ISI/SCOPUS Indexed Publication).
  • MK Sangeetha, HR Balaji Raghavendran, V Gayathri, HR Vasanthi. 2011. Tinospora cordifolia attenuates oxidative stress and distorted carbohydrate metabolism in experimentally induced type 2 diabetes in rats. Journal of natural medicines, 1-7 (ISI/SCOPUS Indexed Publication).
  • HRB Raghavendran, P Srinivasan, S Rekha. 2011. Immunomodulatory activity of fucoidan against aspirin-induced gastric mucosal damage in rats. International immunopharmacology 11 (2), 157-163 (ISI/SCOPUS Indexed Publication).
  • JW Shin, JY Son, HRB Raghavendran, WK Chung, HG Kim, HJ Park, Jang SS. Son GC. 2012. High-dose ionizing radiation-induced hematotoxicity and metastasis in mice model. Clinical and Experimental Metastasis, 1-8 (ISI/SCOPUS Indexed Publication) JY Son, JW Shin, JH Wang, HJ Park, HG Kim, HRB Raghavendran, Son GC. 2010. Chemotherapy-induced myelotoxicity and incidence of lung metastasis in an animal model. Human & experimental toxicology. 30(7):649-55 (ISI/SCOPUS Indexed Publication).
  • HRB Raghavendran, S Rekha, JW Shin, HG Kim, JH Wang, HJ Park, Choi MK, Cho JH, Son GC.2011. Effects of Korean ginseng root extract on cisplatin-induced emesis in a rat-pica model. Food and Chemical Toxicology 49 (1), 215-221 (ISI/SCOPUS Indexed Publication).
  • RP Parameswari, M Vasanthkumar, V Gayathri, VM Manikandamathavan, G Ramakrishnan, MK Sangeetha, V Vijayakumar, H Balaji Raghavendran, D Chamundeeswari, Hannah R Vasanthi. 2010. Prophylactic Role of a Herbomineral Drug “Thamira Parpam” Against Cysteamine-Induced Oxidative Stress in Liver and Duodenum of Rats. Biological trace element research 138 (1-3), 212-225 (ISI/SCOPUS Indexed Publication).
  • Choi JI, Raghavendran HR, Sung NY, Kim JH, Chun BS, Ahn DH, Choi HS, Kang KW, Lee JW. 2010. Effect of fucoidan on aspirin-induced stomach ulceration in rats. Chemico-biological interactions 183 (1), 249-254 (ISI/SCOPUS Indexed Publication).
  • M Vasanthkumar, RP Parameswari, VV Kumar, MK Sangeetha, Gayathri V, Balaji Raghavendran H, Chamundeeswari D, Vasanthi HR. 2010. Anti-ulcer role of herbomineral siddha drug—Thamira parpam on experimentally induced gastric mucosal damage in rats. Human & experimental toxicology 29 (3), 161-173 (ISI/SCOPUS Indexed Publication).
  • Subash Ananthi, Hanumantha Rao Balaji Raghavendran, Adoor Gopalan Sunil, Veeraraghavan Gayathri, Ganapathy Ramakrishnan, Hannah R Vasanthi. In vitro antioxidant and in vivo anti-inflammatory potential of crude polysaccharide from Turbinaria ornata (Marine Brown Alga) Food and Chemical Toxicology 48 (1), 187-192 (ISI-Indexed).
  • Lee JW, Byun EH, Sung NY, Raghavendran HR, Byun EB, Kim JH, Choi JI, Shin MG, Byun MW. 2009. Effect of gamma irradiation on the efficacy of beta-glucan against acetaminophen induced toxicity in mice. Chem Biol Interact. 2009 Jun 15;180(1):98-105. (ISI/SCOPUS Indexed Publication).
  • T Devaki, A Sathivel, HR Balaji Raghavendran. 2009. Stabilization of mitochondrial and microsomal function by polysaccharide of Ulva lactuca on D-Galactosamine induced hepatitis in rats. Chemico-Biological Interactions 177 (2), 83-88 (ISI/SCOPUS Indexed Publication).
  • S Tamilselvi, HB Raghavendran, P Srinivasan, N Rajendran. 2009. In vitro and in vivo studies of alkali-and heat-treated Ti-6Al-7Nb and Ti-5Al-2Nb-1Ta alloys for orthopedic implants. Journal of Biomedical Materials Research Part A 90 (2), 380-386 (ISI/SCOPUS Indexed Publication).
  • JH Kim, NY Sung, HB Raghavendran, Y Yoon, BS Song, J Choi, YC Yoo, Byun WM, Hwang YJ, Lee JW. 2009. Gamma irradiation reduces the immunological toxicity of doxorubicin, anticancer drug. Radiation Physics and Chemistry 78 (7-8), 425-428 (ISI/SCOPUS Indexed Publication).
  • Lee JW, Sung NY, Kim JK, Kim JH, Raghavendran HR, Yoo YC, Shin MH, Byun MW. 2008. Effect of gamma irradiation on spleen cell function and cytotoxicity of doxorubicin. Chem Biol Interact. 2008 Jun 17;173(3):205-14. (ISI/SCOPUS Indexed Publication), P Srinivasan. 2008. Effect of crude sulphated polysaccharide from brown algae against acetaminophen-induced toxicity in rats. Canadian journal of physiology and HRB Raghavendran pharmacology 86 (10), 660-666 (ISI/SCOPUS Indexed Publication).
  • A Sathivel, HRB Raghavendran, P Srinivasan, T Devaki. 2008. Anti-peroxidative and anti-hyperlipidemic nature of Ulva lactuca crude polysaccharide on d-Galactosamine induced hepatitis in rats. Food and Chemical Toxicology 46 (10), 3262-3267 (ISI/SCOPUS Indexed Publication).
  • Raghavendran HB, Sathivel A, Yogeeta RS, Devaki T. 2007. Efficacy of Sargassum polycystum (Phaeophyceae) sulphated polysaccharide against paracetamol-induced DNA fragmentation and modulation of membrane-bound phosphatases during toxic hepatitis. Clin Exp Pharmacol Physiol. 34(3):142-7. (ISI/SCOPUS Indexed Publication).
  • Subashini R, Ragavendran B, Gnanapragasam A, Yogeeta SK, Devaki T. 2007. Biochemical study on the protective potential of Nardostachys jatamansi extract on lipid profile and lipid metabolizing enzymes in doxorubicin intoxicated rats. Pharmazie. 62(5):382-7. (ISI/SCOPUS Indexed Publication).
  • S Yogeeta, HRB Raghavendran, T Devaki. 2007. Antihepatotoxic Effect of Punica granatum. Acetone Extract against Isoniazid-and Rifampicin-Induced Hepatotoxicity. Pharmaceutical Biology 45 (8), 631-637 (ISI/SCOPUS Indexed Publication).
  • Yogeeta SK, Hanumantra RB, Gnanapragasam A, Senthilkumar S, Subhashini R, Devaki T. 2006. Attenuation of abnormalities in the lipid metabolism during experimental myocardial infarction induced by isoproterenol in rats: beneficial effect of ferulic acid and ascorbic acid. Basic Clin Pharmacol Toxicol. 2006 May; 98(5):467-72. (ISI-Indexed).
  • G Ramakrishnan, HRB Raghavendran, R Vinodhkumar, T Devaki. 2006. Suppression of N-nitrosodiethylamine induced hepatocarcinogenesis by silymarin in rats. Chemico-biological interactions 161 (2), 104-114 (ISI/SCOPUS Indexed Publication).
  • SK Yogeeta, HRB Raghavendran, A Gnanapragasam, R Subhashini, Devaki T. 2006. Ferulic acid with ascorbic acid synergistically extenuates the mitochondrial dysfunction during ß-adrenergic catecholamine induced cardiotoxicity in rats. Chemico-biological interactions 163 (1), 160-169 (ISI/SCOPUS Indexed Publication).
  • HB Raghavendran, A Sathivel, T Devaki. 2006. Defensive nature of Sargassum polycystum (Brown alga) against acetaminophen-induced toxic hepatitis in rats: role of drug metabolizing microsomal enzyme system, tumor necrosis factor-alpha and fate of liver cell structural integrity. World journal of gastroenterology: WJG 12 (24), 3829. (ISI/SCOPUS Indexed Publication).
  • G Ramakrishnan, HRB Raghavendran, R Vinodhkumar, T Devaki.Suppression of nitrosodiethylamine induced hepatocarcinogenesis by silymarin in rats Chemico-biological interactions 161 (2), 104-114 (ISI-Indexed).
  • HRB Raghavendran, A Sathivel, T Devaki. 2005. Antioxidant effect of Sargassum polycystum (Phaeophyceae) against acetaminophen induced changes in hepatic mitochondrial enzymes during toxic hepatitis. Chemosphere 61 (2), 276-281 (ISI/SCOPUS Indexed Publication).
  • Raghavendran HRB, A Sathivel, T Devaki. 2005. Effect of Sargassum polycystum (Phaeophyceae)-sulphated polysaccharide extract against acetaminophen-induced hyperlipidemia during toxic hepatitis in experimental rats. Molecular and Cellular Biochemistry 276 (1-2), 89 (ISI/SCOPUS Indexed Publication).
  • HRB Raghavendran, A Sathivel, T Devaki. 2005. Protective effect of Sargassum polycystum (brown alga) against acetaminophen-induced lipid peroxidation in rats. Phytotherapy Research 19 (2), 113-115 (ISI/SCOPUS Indexed Publication).
  • H Balaji Raghavendra Rao, A Sathivel, T Devaki. 2004. Antihepatotoxic nature of Ulva reticulata (Chlorophyceae) on acetaminophen-induced hepatoxicity in experimental rats. Journal of medicinal food 7 (4), 495-497 (ISI/SCOPUS Indexed Publication).
  • HRB Raghavendran, A Sathivel, T Devaki. 2004. Efficacy of brown seaweed hot water extract against HCl-ethanol induced gastric mucosal injury in rats. Archives of pharmacal research 27 (4), 449-453 (ISI/SCOPUS Indexed Publication).
  • HRB Raghavendran, A Sathivel, T Devaki Hepatoprotective nature of seaweed alcoholic extract on acetaminophen induced hepatic oxidative stress Journal Of Health Science-Tokyo- 50 (1), 42-46 (ISI-Indexed).

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