- Dr. Pouya Hassandarvish has completed his Ph.D. study in the field of Medical Microbiology sponsored by The University of Malaya under the Bright Spark scholarship. Along with my master’s degree in the field of Biomedical Science.
- Dr. Pouya Hassandarvish completed his bachelor’s degree in the field of Marine Biology from Azad University Iran.
- He is currently promoted as Senior Lecturer in TIDREC@UM.
- Before this, he is working as a Postdoctoral research fellow in TIDREC and managed the antiviral drug discovery lab at University Malaya.
Over the past 13 years, Dr. Pouya Hassandarvish has worked on:
- Arthropod viruses such as Dengue, Chikungunya, Zika, and Japanese Encephalitis. Other viruses such as SARS-CoV-2, H1N1, H3N2.
- TIDREC Team member for COVID19 Vaccine development.
- Trained undergraduate students and postgraduate students.
- Been exposed to a lot of experiments and skills related to the field such as Immunology, histology and Microbiology.
- Contributed to a lot of research and have attended several international conferences overseas.
- Handled projects related to Antiviral, Antibacterial, diabetes, wound healing, stomach ulcer, liver cirrhosis and vivo & vitro cancer study. (Colon cancer, leukaemia and breast cancer).
- Kim-Ling Chin, Nurhafiza Zainal, Sing-Sin Sam, Pouya Hassandarvish, Rafidah Lani , Sazaly AbuBakar. Intracellular translocation of HMGB1 is important for Zika virus replication in Huh7 cells. Scientific Reports. 2022.
- Chee-Sieng Khor, Ryohei Tsuji, Hai-Yen Lee, Siti-Sarah Nor’e, Norhidayu Sahimin, Adzzie-Shazleen Azman, Vunjia Tiong, Pouya Hasandarvish, Boon-Teong Teoh, Yih-Harng Soh, Jian-Hai Chai, Takeshi Kokubo, Osamu Kanauchi, Naoki Yamamoto and Sazaly AbuBakar. Lactococcus lactis Strain Plasma Intake Suppresses the Incidence of Dengue Fever-like Symptoms in Healthy Malaysians: A Randomized, Double-Blind, Placebo-Controlled Trial. Nutrients. 2021.
- Low Zhao Xuan, Ming Ou Yong , Pouya Hassandarvish, Poh Chit Laa, and Babu Ramanathan. Antiviral activity of silymarin and baicalein against dengue virus. Scientific Reports. 2021.
- Vunjia Tiong, Pouya Hassandarvish, Sazaly Abu Bakar, Nurul Azmawati Mohamed, Wan Shahida Wan Sulaiman, Nizam Baharom, Farishah Nur Abdul Samad, Ilina Isahak. The Effectiveness of Various Gargle Formulations and Salt Water Against SARS-CoV-2. Scientific Reports. 2021.
- Rafidah Lani, Fatima Ezzahra Agharbaoui, Pouya Hassandarvish, Boon Teong Teoh, Sing Sin Sam, Keivan Zandi, Noorsaadah Abd Rahman & Sazaly AbuBakar. Potential Binding Conformations of Silymarin and Fisetin on the Chikungunya Virus Proteins. Future Virology. 2021.
- Nur-Faralyza Mohd Baharudin, Nur Adila Malek, Nurfatihah Zulkifli, Rafidah Lani, Christina Injan Mawang, Pouya Hassandarvish, Jasmine Elanie Khairat, Adzzie Shazleen Azman. Cytotoxic activity of methanolic extract of Streptomyces sp. strain KSF 83 on growth of human breast and colon cancer cells. Malaysian Journal of Microbiology. 2021.
- Keivan Zandi *, Katie Musall , Adrian Oo , Dongdong Cao , Bo Liang , Pouya Hassandarvish , Shuiyun Lan , Ryan L. Slack , Karen A. Kirby , Leda Bassit , Franck Amblard , Baek Kim , Sazaly AbuBakar , Stefan G. Sarafianos , Raymond F Schinazi. Baicalein and Baicalin inhibit SARS-CoV-2 RNA-dependent-RNA Polymerase. Microorganism. 2021.
- P. Hassandarvish, V. Tiong, N. A. Mohamed. H. Arumugam, A. Ananthanarayanan, M. Qasuri, M. Hadjiat, Sazaly AB. In-vitro Virucidal Activity of Povidone Iodine Gargle and Mouthwash against SARS-CoV-2: Implications in Dental Practice. British Dental Journal. 2020.
- P. Hassandarvish, V. Tiong, A. B. Sazaly, N. A. Mohamed. H. Arumugam, A. Ananthanarayanan, M. Qasuri, M. Hadjiat. Povidone iodine gargle and mouthwash. British Dental Journal. 2020.
- Keivan Zandi, Leda Bassit, Franck Amblard, Bryan Cox, Pouya Hassandarvish, Ehsan Moghaddam, Andrew Yueh, Gisele Libanio Rodrigues, Ingredy Passod-Souza, Vivian Costa, Sazaly AbuBakar, Longhu Zhou, James Kohler, Mauro Teixeira, and Raymond Schinazi. Nucleoside Analogs with Selective Antiviral Activity Against Dengue Fever and Japanese Encephalitis Viruses. Antimicrobial Agents and Chemotherapy. 2019.
- George. A., Zandi, K., Biggins, J., Chinnappan, S., Hassandarvish, P. and Yusof, A. Antiviral activity of a standardized root water extract of Eurycoma longifolia (Physta®) against dengue virus”. Tropical Biomedicine. 2018.
- Golbabapour, Shahram, Hajrezaie, Maryam, Hassandarvish, Pouya, Abdul Majid, Nazia, Hadi, A Hamid A, Nordin, Noraziah, & Abdulla, Mahmood A. Corrigendum to Acute toxicity and gastroprotective role of M. pruriens in ethanol-induced gastric mucosal injuries in rats. BioMed research international, 2018.
- Ismail, Iza Farhana, Golbabapour, Shahram, Hassandarvish, Pouya, Hajrezaie, Maryam, Abdul Majid, Nazia, Kadir, Farkaad A, . . . Abdulla, Mahmood Ameen. Gastroprotective activity of Polygonum chinense aqueous leaf extract on ethanol-induced hemorrhagic mucosal lesions in rats. Evidence-Based Complementary and Alternative Medicine, 2018.
- Omer, Fatima Abdelmutaal Ahmed, Hashim, Najihah Mohd, Ibrahim, Mohamed Yousif, Aldoubi, Abdulmannan F, Hassandarvish, Pouya, Dehghan, Firouzeh, . . . Abdulla, Mahmood Ameen. (2017). Beta-mangostin demonstrates apoptogenesis in murine leukaemia (WEHI-3) cells in vitro and in vivo. BMC complementary and alternative medicine, 17(1), 366.
- Hassandarvish P, Oo A, Jokar A, Zukiwski A, Proniuk S, Abu Bakar S, Zandi K. Exploring the in vitro Potential of Celecoxib Derivative, AR-12 as an Effective Antiviral Compound against four Dengue Virus Serotypes. Journal of Antibacterial Chemotherapy. 2017.
- Hajrezaie M, Paydar M, Looi CY, Moghadamtousi SZ, Hassandarvish P, Salga MS, et al. Apoptotic effect of novel Schiff Based CdCl2 (C14H21N3O2) complex is mediated via activation of the mitochondrial pathway in colon cancer cells. Scientific Reports. 2017.
- Omar, Hanita, Nordin, Noraziah, Hassandarvish, Pouya, Hajrezaie, Maryam, Azizan, Ainnul Hamidah Syahadah, Fadaeinasab, Mehran, . . . Ali, Hapipah Mohd. Methanol leaf extract of Actinodaphne sesquipedalis (Lauraceae) enhances gastric defense against ethanol-induced ulcer in rats. Drug design, development and therapy. 2017.
- Al-Wajeeh, Nahla Saeed, Hajerezaie, Maryam, Noor, Suzita Mohd, Halabi, Mohammed Farouq, Al-Henhena, Nawal, Azizan, Ainnul Hamidah Syahadah, Hassandarvish, Pouya, Ali, Hapipah Mohd. (2016). The gastro protective effects of Cibotium barometz hair on ethanol-induced gastric ulcer in Sprague-Dawley rats. BMC veterinary research, 13(1), 27.
- Oo, A., Hassandarvish, P., Chin, S. P., Lee, V. S., Bakar, S. A., & Zandi, K. In silico study on anti-Chikungunya virus activity of hesperetin. PeerJ, 4, e2602.2016.
- Lani R, Hassandarvish P, Shu M-H, Phoon WH, Chu JJH, Higgs S, et al. Antiviral activity of selected flavonoids against Chikungunya virus. Antiviral Research. 2016;133:50-61.
- Seyedi SS, Shukri M, Hassandarvish P, Oo A, Muthu SE, Abubakar S, et al. Computational Approach Towards Exploring Potential Anti-Chikungunya Activity of Selected Flavonoids. Scientific reports. 2016;6.
- Ahmadi A, Hassandarvish P, Lani R, Yadollahi P, Jokar A, Bakar SA, et al. Inhibition of chikungunya virus replication by hesperetin and naringenin. RSC Advances. 2016;6(73):69421-30.
- Hassandarvish P, Rothan HA, Rezaei S, Yusof R, Abubakar S, Zandi K. In silico study on baicalein and baicalin as inhibitors of dengue virus replication. RSC Advances. 2016;6(37):31235-47.
- Salim LZA, Othman R, Abdulla MA, Al-Jashamy K, Ali HM, Hassandarvish P, et al. Thymoquinone inhibits murine leukemia WEHI-3 cells in vivo and in vitro. PloS one. 2014;9(12):e115340.
- Al-Henhena N, Khalifa SA, Ying RPY, Hassandarvish P, Rouhollahi E, Al-Wajeeh NS, et al. Chemopreventive effects of Strobilanthes crispus leaf extract on azoxymethane-induced aberrant crypt foci in rat colon. Scientific reports. 2015;5.
- Hajrezaie M, Shams K, Moghadamtousi SZ, Karimian H, Hassandarvish P, Emtyazjoo M, et al. Chemoprevention of colonic aberrant crypt foci by novel Schiff based dichlorido (4-methoxy-2-{[2-(piperazin-4-ium-1-yl) ethyl] iminomethyl} phenolate) Cd complex in azoxymethane-induced colorectal cancer in rats. Scientific reports. 2015;5.
- Lani R, Hassandarvish P, Chiam CW, Moghaddam E, Chu JJH, Rausalu K, et al. Antiviral activity of silymarin against chikungunya virus. Scientific reports. 2015;5.
- NS Gwaram, P Hassandarvish. In silico inhibitory activity against caspase 3 by zinc (II) coordinated complexes. International Journal of Biochemistry Research & Review. 2015.
- Amin, Zahra A, Ali, Hapipah M, Alshawsh, Mohammed A, Pouya Hassandarvish & Abdulla, Mahmood A. Application of Antrodia camphorata promotes rat’s wound healing in vivo and facilitates fibroblast cell proliferation in vitro. Evidence-Based Complementary and Alternative Medicine, 2015.
- Zahedifard, Maryam, Lafta Faraj, Fadhil, Paydar, Mohammadjavad, Yeng Looi, Chung, Hasandarvish, Pouya, Hajrezaie, Maryam, . . . Mohd Ali, Hapipah. Synthesis of apoptotic new quinazolinone-based compound and identification of its underlying mitochondrial signalling pathway in breast cancer cells. Current pharmaceutical design, 21(23), 3417-3426. 2015.
- Salim, Landa Zeenelabdin Ali, Othman, Rozana, Abdulla, Mahmood Ameen, Al-Jashamy, Karim, Ali, Hapipah Mohd, Hassandarvish, Pouya, . . . Mohan, Syam. (2014). Thymoquinone inhibits murine leukemia WEHI-3 cells in vivo and in vitro. PLoS One, 9(12), e115340.
- Nordin, Noraziah, Salama, Suzy Munir, Golbabapour, Shahram, Hajrezaie, Maryam, Hassandarvish, Pouya, Kamalidehghan, Behnam, . . . Fadaienasab, Mehran. Anti-ulcerogenic effect of methanolic extracts from Enicosanthellum pulchrum (King) Heusden against ethanol-induced acute gastric lesion in animal models. PLoS One, 9(11), e111925. 2014.
- Bardi, Daleya Abdulaziz, Halabi, Mohammed Farouq, Hassandarvish, Pouya, Rouhollahi, Elham, Paydar, Mohammadjavad, Moghadamtousi, Soheil Zorofchian, . . . Abdulla, Mahmood Ameen. (2014). Andrographis paniculata leaf extract prevents thioacetamide-induced liver cirrhosis in rats. PLoS One, 9(10), e109424
- Nura Suleiman Gwaram, Pouya Hassandarvish. Synthesis, characterization and anticancer studies of some morpholine derived Schiff bases and their metal complexes. J. Appl. Pharm. Sci. 2014.
- Soheil Zorofchian Moghadamtousi, Habsah Abdul Kadir, Pouya Hassandarvish, Hassan Tajik, Sazaly Abubakar, Keivan Zandi. A review on antibacterial, antiviral, and antifungal activity of curcumin. BioMed research international. 2014.
- Al-Obaidi, Mazen M Jamil, Al-Bayaty, Fouad Hussain, Al Batran, Rami, Hassandarvish, Pouya, & Rouhollahi, Elham. Protective effect of ellagic acid on healing alveolar bone after tooth extraction in rat—a histological and immunohistochemical study. Archives of oral biology, 59(9), 987-999. 2014.
- Shawish, Hana Bashir, Wong, Wan Ying, Wong, Yi Li, Loh, Sheng Wei, Looi, Chung Yeng, Hassandarvish, Pouya, . . . Paterson, Ian C. Nickel (II) complex of polyhydroxybenzaldehyde N4-thiosemicarbazone exhibits anti-inflammatory activity by inhibiting NF-κB transactivation. PLoS One, 9(6), e100933. 2014
- Moghaddam E, Teoh B-T, Sam S-S, Lani R, Hassandarvish P, Chik Z, et al. Baicalin, a metabolite of baicalein with antiviral activity against dengue virus. Scientific reports. 2014;4.
- Halabi, Mohammed Farouq, Shakir, Raied Mustafa, Bardi, Daleya Abdulaziz, Al-Wajeeh, Nahla Saeed, Ablat, Abdulwali, Hassandarvish, Pouya, . . . Abdulla, Mahmood Ameen. Gastroprotective activity of ethyl-4-[(3, 5-di-tert-butyl-2-hydroxybenzylidene) amino] benzoate against ethanol-induced gastric mucosal ulcer in rats. PLoS One, 9(5), e95908. 2014.
- Al-Obaidi, Mazen M Jamil, Al-Bayaty, Fouad Hussain, Al-Batran, Rami, Abdulla, Mahmood Ameen, Hassandarvish, Pouya, Ariffin, Farha, & Hussain, Jamal. Evaluation of the Potential Effect of Ellagic Acid on Cotinine and Antioxidant Levels in Nicotine-Induced Rats. International Medical Journal, 21(2). 2014.
- Hajrezaie M, Hassandarvish P, Moghadamtousi SZ, Gwaram NS, Golbabapour S, NajiHussien A, et al. Chemopreventive evaluation of a Schiff base derived copper (II) complex against azoxymethane-induced colorectal cancer in rats. PloS one. 2014;9(3):e91246.
- Razmavar S, Abdulla MA, Ismail SB, Hassandarvish P. Antibacterial activity of leaf extracts of Baeckea frutescens against methicillin-resistant Staphylococcus aureus. BioMed research international. 2014;2014.
- Syam, Suvitha, Bustamam, Ahmad, Abdullah, Rasedee, Aspollah Sukari, Mohamed, Mohd Hashim, Najihah, Yahayu, Maizatulakmal, Hassandarvish, Pouya, Ibrahim Abdelwahab, Siddig. (2014). Cytotoxicity and Oral Acute Toxicity Studies of β-mangostin Isolated from Cratoxylum arborescens. Pharmacognosy Journal, 6(1).
- Rahim, Nurhidayah Ab, Hassandarvish, Pouya, Golbabapour, Shahram, Ismail, Salmah, Tayyab, Saad, & Abdulla, Mahmood Ameen. Gastroprotective effect of ethanolic extract of Curcuma xanthorrhiza leaf against ethanol-induced gastric mucosal lesions in Sprague-Dawley rats. BioMed research international, 2014.
- Hajrezaie, Maryam, Paydar, Mohammadjavad, Zorofchian Moghadamtousi, Soheil, Hassandarvish, Pouya, Gwaram, Nura Suleiman, Zahedifard, Maryam, . . . Ali, Hapipah Mohd. (2014). A Schiff Base-derived copper (II) complex is a potent inducer of apoptosis in colon cancer cells by activating the intrinsic pathway. The Scientific World Journal, 2014.
- Ibrahim AA, Khaledi H, Hassandarvish P, Ali HM, Karimian H. Indole-7-carbaldehyde thiosemicarbazone as a flexidentate ligand toward Zn II, Cd II, Pd II and Pt II ions: cytotoxic and apoptosis-inducing properties of the Pt II complex. Dalton Transactions. 2014;43(10):3850-60.
- Dhiyaaldeen, Summaya M, Amin, Zahra A, Pouya Hassandarvish, Mustafa, Iman Fahmi, Jamil, Mazen M, Rouhollahi, Elham, & Abdulla, Mahmood A. Protective effects of (1-(4-hydroxy-phenyl)-3-m-tolyl-propenone chalcone in indomethacin-induced gastric erosive damage in rats. BMC veterinary research, 10(1), 961. 2014.
- Salama, Suzy M, AlRashdi, Ahmed S, Abdulla, Mahmood A, Hassandarvish, Pouya, & Bilgen, Mehmet. Protective activity of Panduratin A against Thioacetamide-induced oxidative damage: demonstration with in vitro experiments using WRL-68 liver cell line. BMC complementary and alternative medicine, 13(1), 279. 2013.
- Shahram Golbabapour, Maryam Hajrezaie, Pouya Hassandarvish, Nazia Abdul Majid, A Hamid A Hadi, Noraziah Nordin, Mahmood A Abdulla. Acute toxicity and gastroprotective role of M. pruriens in ethanol-induced gastric mucosal injuries in rats. BioMed Research International. 2013.
- Golbabapour, Shahram, Gwaram, Nura Suleiman, Hassandarvish, Pouya, Hajrezaie, Maryam, Kamalidehghan, Behnam, Abdulla, Mahmood Ameen, . . . Majid, Nazia Abdul. Gastroprotection studies of Schiff base zinc (II) derivative complex against acute superficial hemorrhagic mucosal lesions in rats. PLoS One, 8(9), e75036. 2013.
- Al Batran, Rami, Al‐Bayaty, Fouad, Ameen Abdulla, Mahmood, Al‐Obaidi, Jamil, Mazen, M, Hajrezaei, Maryam, Hassandarvish, Pouya, Talaee, Samaneh.Gastroprotective effects of Corchorus olitorius leaf extract against ethanol‐induced gastric mucosal hemorrhagic lesions in rats. Journal of gastroenterology and hepatology, 28(8), 1321-1329. 2013.
- Sidahmed, Heyam MA, Hashim, Najihah Mohd, Amir, Junaidah, Abdulla, Mahmood Ameen, Hadi, A Hamid A, Abdelwahab, Siddig Ibrahim, Hassandarvish, Pouya, Loke, Mun Fai. (2013). Pyranocycloartobiloxanthone A, a novel gastroprotective compound from Artocarpus obtusus Jarret, against ethanol-induced acute gastric ulcer in vivo. Phytomedicine, 20(10), 834-843.
- Golbabapour S, Majid NA, Hassandarvish P, Hajrezaie M, Abdulla MA, Hadi AHA. Gene silencing and Polycomb group proteins: an overview of their structure, mechanisms and phylogenetics. Omics: a journal of integrative biology. 2013;17(6):283-96.
- Ketuly, Kamal A, Hadi, A Hamid A, Golbabapour, Shahram, Hajrezaie, Maryam, Hassandarvish, Pouya, Ali, Hapipah Mohd, . . . Abdulla, Mahmood A. (2013). Acute toxicity and gastroprotection studies with a newly synthesized steroid. PLoS One, 8(3), e59296.
- Hajrezaie, Maryam, Golbabapour, Shahram, Hassandarvish, Pouya, Gwaram, Nura Suleiman, Hadi, A Hamid A, Ali, Hapipah Mohd, . . . Abdulla, Mahmood Ameen. Acute toxicity and gastroprotection studies of a new schiff base derived copper (II) complex against ethanol-induced acute gastric lesions in rats. PLoS One, 7(12), e51537.2012.
- Gwaram, Nura Suleiman, Ali, Hapipah Mohd, Saharin, Siti Munirah, Abdulla, Mahmood Ameen, Hassandarvish, Pouya, Lin, Thong Kwai, . . . Ooi, Cher Lin. Synthesis, characterization, and biological applications of some 2-acetylpyridine and acetophenone derivatives. Journal of Applied Pharmaceutical Science 2. 2012.
- Ibrahim, Mohamed Mustafa, Ali, Hapipah Mohd, Abdullah, Mahmood Ameen, & Hassandarvish, Pouya. Acute toxicity and gastroprotective effect of the Schiff base ligand 1H-indole-3-ethylene-5-nitrosalicylaldimine and its nickel (II) complex on ethanol induced gastric lesions in rats. Molecules, 17(10), 12449-12459. 2012.
- Gwaram, Nura Suleiman, Ali, Hapipah Mohd, Abdulla, Mahmood Ameen, Buckle, Michael JC, Sukumaran, Sri Devi, Chung, Lip Yong, Hassandarvish, Pouya, Hadi, A Hamid A. Synthesis, characterization, X-ray crystallography, acetyl cholinesterase inhibition and antioxidant activities of some novel ketone derivatives of gallic hydrazide-derived Schiff bases. Molecules, 17(3), 2408-2427. 2012.
- Al-Mamary, Mohammed, Abdelwahab, Siddig Ibrahim, Ali, Hapipah Mohd, Ismail, Salma, Abdulla, Mahmood Ameen, & Darvish, Pouya. (2012). Synthesis, antioxidant and antibacterial activities of some schiff bases containing hydroxyl and methoxy groups. Asian Journal of Chemistry, 24(10), 4335.
- Khaledi, Hamid, Alhadi, Abeer A, Yehye, Wagee A, Ali, Hapipah Mohd, Abdulla, Mahmood A, & Hassandarvish, Pouya. Antioxidant, Cytotoxic Activities, and Structure–Activity Relationship of Gallic Acid‐based Indole Derivatives. Archiv der Pharmazie, 344(11), 703-709. 2011.
- Muhammad Saleh Salga, Hapipah Mohd Ali, Mahmood Ameen Abdullah, Siddig Ibrahim Abdelwahab, Pouya Hassandarvish, A Hamid A Hadi. Mechanistic studies of the anti-ulcerogenic activity and acute toxicity evaluation of dichlorido-copper (II)-4-(2-5-Bromo-benzylideneamino) ethyl) piperazin-1-ium phenolate. Molecules. 2011.
- Kadir, Farkaad A, Othman, Faizah, Abdulla, Mahmood Ameen, Hussan, Farida, & Hassandarvish, Pouya. (2011). Effect of Tinospora crispa on thioacetamide-induced liver cirrhosis in rats. Indian journal of pharmacology, 43(1), 64.
- Fouad Al-Bayaty, Mahamood Abdulla, Pouya Hassandarvish. Evaluation of hyaluronate anti-ulcer activity against gastric mucosal injury. African Journal of Pharmacy and Pharmacology. 2011.
- Alrdahe, Salma Saleh, Abdulla, Mahmood Ameen, Razak, Shaharudin Abul, Kadir, Farkaad Abdul, & Hassandarvish, Pouya. Gastroprotective activity of Swietenia mahagoni seed extract on ethanol-induced gastric mucosal injury in rats. World Acad Sci Eng Technol, 43, 883-887. 2010.
- Ameen Abdulla Mahmood, Hassandarvish Pouya, Mohd Ali Hapipah, Mohd Noor Suzita, Hussain Mahmoud Fouad, Syuhada Nor, Haji Rokik Rosaimawati, WI Khalil. Acceleration of wound healing potential by Lantana camara leaf extract in experimental rats. Research Journal of Medical Sciences.
